DHE if you have uncontrolled high blood pressure, heart disease or certain other medical problems. IMITREX may cause serious side effects. See “What is the most important information I should know about IMITREX? Significant elevation in blood pressure, including hypertensive crisis with acute impairment of organ systems, has been reported on rare occasions in patients treated with 5-HT 1 agonists, including patients without a history of hypertension. Monitor blood pressure in patients treated with IMITREX. Imitrex Injection is contraindicated in patients with uncontrolled hypertension.
Some people may have feelings of tingling, heat, flushing redness of face lasting a short time heaviness or pressure after treatment with IMITREX Injection. A few people may feel drowsy, dizzy, tired, or sick. Tell your doctor of these symptoms at your next visit. Neurological: Central nervous system vasculitis, cerebrovascular accident, dysphasia, subarachnoid hemorrhage. Ask your healthcare provider if you should take your first dose in a medical setting. Imitrex Injection is not indicated for the prevention of migraine or cluster headache attacks. If you do not get relief from the first dose of this medicine, do not take a second dose without first talking to your healthcare provider.
Tell your doctor if you are or if you plan to become pregnant. It is recommended that patients who are intermittent long-term users of sumatriptan and who have or acquire risk factors predictive of CAD, as described above, undergo periodic interval cardiovascular evaluation as they continue to use sumatriptan. In considering this recommendation for periodic cardiovascular evaluation, it is noted that patients with cluster headache are predominantly male and over 40 years of age, which are risk factors for CAD. IMITREX. Such reactions can be life threatening or fatal. In general, anaphylactic reactions to drugs are more likely to occur in individuals with a history of sensitivity to multiple allergens. Imitrex Injection is contraindicated in patients with a history of hypersensitivity reaction to IMITREX.
Take the new Cartridge Pack out of its box. It began on Saturday, and by that evening I experienced the worst headache I've ever had. Sumatriptan may also be used for purposes not listed in this medication guide. What is the most important information I should know about Imitrex Statdose sumatriptan injection?
Imitrex tablets are not approved for use in CHILDREN younger than 18 years old. Talk with the doctor. The name of your medicine is IMITREX sumatriptan succinate Injection. It can be obtained only by prescription from your doctor. The decision to use IMITREX Injection is one that you and your doctor should make jointly, taking into account your individual preferences and medical circumstances. If you have risk factors for heart disease such as high blood pressure, high cholesterol, obesity, diabetes, smoking, strong family history of heart disease, or you are postmenopausal or a male over 40 you should tell your doctor, who should evaluate you for heart disease in order to determine if IMITREX is appropriate for you. Although the vast majority of those who have taken IMITREX have not experienced any significant side effects, some individuals have experienced serious heart problems and, rarely, considering the extensive use of IMITREX worldwide, deaths have been reported. In all but a few instances, however, serious problems occurred in people with known heart diseases and it was not clear whether IMITREX was a contributory factor in these deaths. The incidence of adverse reactions in controlled clinical trials was not affected by gender or age of the patients. There were insufficient data to assess the impact of race on the incidence of adverse reactions. Call your doctor for medical advice about side effects. This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Your dosage is based on your medical condition and response to therapy. Tell your doctor if your condition does not improve or worsens. What should I avoid while taking Imitrex? Cerebral hemorrhage, subarachnoid hemorrhage, and stroke have occurred with 5-HT1 treatment; some have resulted in fatalities. One case of sumatriptan-induced cortical stroke has been reported in a patient with sagittal sinus thrombosis. In some cases, it appears possible that the cerebrovascular events were primary, and the 5-HT1 agonist administered in the belief that presenting symptoms were due to migraine when they were not. Patients with migraine may also be at an increased risk of certain cerebrovascular events such as stroke, hemorrhage, and transient ischemic attacks. Parenteral drug products should be inspected visually for particulate matter and discoloration before administration whenever solution and container permit. Life-threatening disturbances of cardiac rhythm, including ventricular tachycardia and ventricular fibrillation leading to death, have been reported within a few hours following the administration of 5-HT 1 agonists. Discontinue Imitrex Injection if these disturbances occur. Imitrex Injection is contraindicated in patients with Wolff-Parkinson-White syndrome or arrhythmias associated with other cardiac accessory conduction pathway disorders.
No gross overdoses in clinical practice have been reported. Incidence in Controlled Clinical Trials of Migraine Headache: Table 4 lists adverse events that occurred in 2 large US, Phase III, placebo-controlled clinical trials in migraine patients following either a single dose of IMITREX Injection or placebo. Imitrex Injection should continue for at least 10 hours or while symptoms or signs persist. Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Pen from accidentally firing until you are ready. This drug may make you dizzy or drowsy. not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid beverages. Heart attack and other heart problems. Heart problems may lead to death. Different brands of this medication have different storage needs. Check the product package for instructions on how to store your brand, or ask your pharmacist. Keep all medications away from children and pets. dutasteride
Overall, the frequency of adverse reactions reported in the trials of cluster headache was generally lower than in the migraine trials. Exceptions include reports of paresthesia 5% Imitrex Injection, 0% placebo nausea and vomiting 4% Imitrex Injection, 0% placebo and bronchospasm 1% Imitrex Injection, 0% placebo. The use of Imitrex Tablets is contraindicated in patients with ischemic or vasospastic CAD. There have been rare reports of serious cardiac adverse reactions, including acute myocardial infarction, occurring within a few hours following administration of Imitrex Tablets. Some of these reactions occurred in patients without known CAD. Endocrine and Metabolic: Elevated thyrotropin stimulating hormone TSH levels; endocrine cysts, lumps, and masses; fluid disturbances; galactorrhea; hyperglycemia; hypoglycemia; hypothyroidism; weight gain; and weight loss. Do not start, stop, or change the dosage of any medicines without your doctor's approval. When did your headaches first start? Sumatriptan is used to treat migraine headaches. Sumatriptan will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks. Call your doctor if your headache does not go away at all after using the first sumatriptan dose. The trials did not establish the efficacy of IMITREX Nasal Spray compared with placebo in the treatment of migraine in pediatric patients. Adverse reactions observed in these clinical trials were similar in nature to those reported in clinical trials in adults. How would you describe the pain: throbbing, stabbing, blinding, or piercing, for example? wazam.info domperidone
Care should be taken to exclude other potentially serious neurologic conditions before treating headache in patients not previously diagnosed with migraine or cluster headache or who experience a headache that is atypical for them. There have been rare reports where patients received sumatriptan for severe headaches that were subsequently shown to have been secondary to an evolving neurologic lesion see . For a given attack, if a patient does not respond to the first dose of sumatriptan, the diagnosis of migraine or cluster headache should be reconsidered before administration of a second dose. After using sumatriptan nasal spray, you must wait two 2 hours before using a second spray. Do not use more than 40 mg of sumatriptan nasal spray in 24 hours. What happens if I overdose? Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. 'Multum' is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Tablets: White, triangular-shaped, film-coated, and debossed with “I” on one side and “25” on the other. Number of headaches treated. Single doses of 5, 10, or 20 mg of Imitrex Nasal Spray administered into 1 nostril were effective for the acute treatment of migraine in adults. PREGNANCY and BREAST-FEEDING: It is not known if Imitrex tablets can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Imitrex tablets while you are pregnant. Imitrex tablets are found in breast milk. If you are or will be breast-feeding while you use Imitrex tablets, check with your doctor. Discuss any possible risks to your baby. Do not flush down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. As you age, it is normal to experience some memory lapses. Usually, an occasional memory lapse does not mean you have a serious problem. Do you have risk factors for heart disease such as high blood pressure, high cholesterol, obesity, diabetes, smoking, strong family history of heart disease, or you are postmenopausal or a male over 40? Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Increase in Blood Pressure: Significant elevation in blood pressure, including hypertensive crisis, has been reported on rare occasions in patients with and without a history of hypertension. Sumatriptan is contraindicated in patients with uncontrolled hypertension see . Sumatriptan should be administered with caution to patients with controlled hypertension as transient increases in blood pressure and peripheral vascular resistance have been observed in a small proportion of patients. brand anafranil generico
Chest discomfort is usually noncardiac in origin. A survey of 453 migraine patients found chest symptoms occurred in up to 58% of patients in at least some attacks and in up to 42% of patients in all attacks. Eye: Accommodation disorders, blindness and low vision, conjunctivitis, disorders of sclera, external ocular muscle disorders, eye edema and swelling, eye hemorrhage, eye itching, eye pain, keratitis, mydriasis, and visual disturbances. Imitrex Injection is a clear, colorless to pale yellow, sterile, nonpyrogenic solution for subcutaneous injection. There are many reasons why people have trouble taking their medicine. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; bloody diarrhea; burning or aching in your feet or toes; burning, numbness, or tingling; constipation; diarrhea; fainting; feeling of heaviness or tightness in your leg muscles; fever; hearing problems; leg cramps; seizures; severe or persistent headache, dizziness, nausea, or vomiting; severe stomach pain; very cold or blue fingers or toes; vision changes or loss of vision; weight loss; wheezing. An extra patient leaflet is available with Imitrex tablets. Talk to your pharmacist if you have questions about this information. AMERGE, IMITREX, IMITREX STATdose System, and IMITREX STATdose Pen are registered trademarks of the GSK group of companies. The other brands listed are trademarks of their respective owners and are not trademarks of the GSK group of companies. The makers of these brands are not affiliated with and do not endorse the GSK group of companies or its products. Serious cardiac events, including some that have been fatal, have occurred following the use of IMITREX Injection or Tablets. These events are extremely rare and most have been reported in patients with risk factors predictive of CAD. Rare were herpes, swelling of face, sweating, and peeling of skin. Ask your health care provider any questions you may have about how to use Imitrex spray. Seizures have been reported in patients with either a history of seizures or concurrent conditions predisposing to seizures and also in patients where no such predisposing factors are apparent. Since sumatriptan is used as needed, it does not have a daily dosing schedule. Call your doctor promptly if your symptoms do not improve after using sumatriptan. IMITREX Injection 1 hour after the initial injection. Treatment of migraine attacks with sumatriptan. the subcutaneous sumatriptan international study group. Loss of vision included reports of permanent defects. Causality has not been established as visual disorders may occur during a migraine attack itself. generic pyridostigmine kada
If you did not get any relief after the first injection, do not give a second injection without first talking with your healthcare provider. Treatment should be started at the first sign of a migraine headache, or associated symptoms such as nausea, vomiting, or photophobia; this drug should not be used for migraine prophylaxis. Review all your prescription and nonprescription and dosages with your doctor or pharmacist. Many medicines, by themselves or in combination with other medicines, can cause mental confusion. Also, confusion may occur when medicines interact in your body. If you see several doctors, make sure that they all know what other medicines you are taking. Have all of your filled at the same pharmacy. Ask your doctor or pharmacist whether the combination of your medicines could cause problems. Teratogenicity: Term fetuses from Dutch Stride rabbits treated during organogenesis with oral sumatriptan exhibited an increased incidence of cervicothoracic vascular and skeletal abnormalities. The functional significance of these abnormalities is not known. General information about the safe and effective use of Imitrex. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. The goal: Choose what works, use it first, and use it fast.
HT 1 agonists. Since visual disorders may be part of a migraine attack, a causal relationship between these events and the use of 5-HT 1 agonists have not been clearly established. Prompt treatment helps you return to your normal routine and may decrease your need for other pain medications. Sumatriptan belongs to a class of drugs known as triptans. It affects a certain natural substance serotonin that causes narrowing of blood vessels in the brain. It may also relieve pain by affecting certain nerves in the brain. IMITREX Nasal Spray sumatriptan nasal spray is generally well tolerated. Across all doses, most adverse reactions were mild and transient and did not lead to long-lasting effects. The incidence of adverse events in controlled clinical trials was not affected by gender, weight, or age of the patients; use of prophylactic medications; or presence of aura. There were insufficient data to assess the impact of race on the incidence of adverse events. IMITREX STAT dose System NDC 0173-0739-02. Sumatriptan may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. antabuse
Product Information. Alsuma SUMAtriptan. Is a trip to the hospital needed? Do not take more than the amount prescribed by your doctor in a 24-hour period or treat more than 4 headaches within 30 days without checking with your doctor. The unit contains only 1 spray. Do NOT test it before use. Six of these 8 patients had ECG changes consistent with transient ischemia, but without accompanying clinical symptoms or signs. Of these 8 patients, 4 had either findings suggestive of CAD or risk factors predictive of CAD prior to study enrollment. Pull the empty Pen out of the Cartridge Pack. cheapest estreva buy pharmacy
This should not be taken if you have certain medical conditions. Keep Imitrex and all medicines out of the reach of children. Cardiovascular: Atrial fibrillation, cardiomyopathy, colonic ischemia see Prinzmetal variant angina, pulmonary embolism, shock, thrombophlebitis. The safety of treating an average of more than 4 headaches in a 30-day period has not been established. Some MEDICINES MAY INTERACT with Imitrex spray. Contact your doctor if you have more than four headaches in one month 30 days. Tell your doctor if this medicine seems to stop working as well in treating your migraine attacks. Incidence in Controlled Trials of Cluster Headache: In the controlled clinical trials assessing sumatriptan's efficacy as a treatment for cluster headache, no new significant adverse events associated with the use of sumatriptan were detected that had not already been identified in association with the drug's use in migraine. Do not consider Communities as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. IMITREX STATdose System NDC 0173-0478-00. buy probalan safely
If side effects still bother you and you wonder if you should keep taking the medicine, call your doctor. He or she may be able to lower your dose or change your medicine. Imitrex is a registered trademark of the GlaxoSmithKline group of companies. Avoid for at least 12 hours after using sumatriptan. Consult your doctor before -feeding. Most people will get daily headaches for 2 weeks to 3 months; in between these periods, they'll be pain-free for at least 2 weeks. About 2 of every 10 people with cluster headaches have less than 14 headache-free days per year. The Pen is now ready to use. Take one sumatriptan tablet whole with a full glass of water. Do not split the tablet. This may not be a complete list of all interactions that may occur. Ask your health care provider if Imitrex tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. Clinical trials of Imitrex Injection did not include sufficient numbers of patients 65 years of age and older to determine whether they respond differently from younger patients. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function and of concomitant disease or other drug therapy. truvada
The product samples shown here have been supplied by the manufacturer. While every effort has been made to assure accurate reproduction, please remember that any visual identification should be considered preliminary. In cases of poisoning or suspected overdosage, the drug's identity should be verified by chemical analysis. Urogenital: Acute renal failure. If your symptoms are only partly relieved or your headache returns, 2 hours after the injection you may switch to sumatriptan taken by mouth instead of using a second injection. After the initial injection you may take sumatriptan by mouth every 2 hours if needed to a maximum of 100 milligrams of tablets in a 24-hour period. Meds that can ease migraine pain as it's happening are called “acute” treatments. Anti-nausea medications. These drugs may help you absorb your pain medication. One will often wake you up an hour or two after you go to bed. Nighttime attacks can be more severe than the daytime ones. The treatment of migraine headaches with or without aura eg, flashing lights, wavy lines, dark spots. It may also be used for other conditions as determined by your doctor. Migraines: One type of drug, called triptans, is the mainstay of migraine treatment. They include eletriptan Relpax naratriptan Amerge rizatriptan Maxalt sumatriptan Imitrex, Zecuity zolmitriptan Zomig and others. BM, but not one that wouldn't go away within 15-20 mins after. It was a 10 out of 10 pain and I was wailing in pain and could not just stay in a dark room and try and sleep it out. I had my Mom come check on me and she looked up this page and read your post, which told us that hopefully it was just a very very intense migraine, but just be be sure we called my doctor and he instructed us to call the ambulance. If you have a higher risk for problems see Precautions your doctor may perform a exam before you start taking this medication. Combination painkillers. Acetaminophen, aspirin, and caffeine combined into one pill are a safe option for people with blood vessel problems. These drugs are similar to the in this medication and may increase your risk of side effects if taken together. However, if your doctor has directed you to take low-dose to prevent or usually at dosages of 81-325 milligrams a day you should continue taking the aspirin unless your doctor instructs you otherwise. The onset of symptoms usually occurs within minutes to hours of receiving a new or a greater dose of a serotonergic medication. Discontinue Imitrex Injection if serotonin syndrome is suspected. Imitrex Tablets. Such reactions can be life threatening or fatal.
Renal Impairment: The effect of renal impairment on the pharmacokinetics of sumatriptan has not been examined. It is unknown what effect hemodialysis or peritoneal dialysis has on the serum concentrations of sumatriptan. Imitrex Injection sumatriptan succinate is a selective serotonin receptor agonist used to treat headaches. Imitrex is available as a generic drug. Pen ready for the next use. Imitrex spray should be inhaled into the nose. Do not get it in your mouth or eyes. If you get it in your eyes, rinse right away with cool tap water. IMITREX. Such reactions can be life threatening or fatal. It is best to take a dose of Imitrex tablets as soon as you notice symptoms of a migraine attack. Pediatric Use: Safety and effectiveness of IMITREX Injection in pediatric patients under 18 years of age have not been established; therefore, IMITREX Injection is not recommended for use in patients under 18 years of age. AUC corresponding to a 40% increase in elimination half-life. No significant effect was seen with an MAO-B inhibitor. Remove STAT dose Pen from s kin. IMITREX in patients with migraine. order generic dostinex payment usa
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But doctors have found that inhaling pure oxygen can work very well to bring relief. Pain medicine such as that goes inside the nose helps some people. Ask your healthcare provider or pharmacist for a list of these medicines if you are not sure. Sumatriptan can pass into breast milk and may harm a nursing baby. Do not breast-feed within 12 hours after using sumatriptan. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby. Schoenen J, Bulcke J, Caekebeke J, Dehaene I, Dekeyser J, Hildebrand G, Joffroy A, Laloux P, Louis P, Monseu G, Pierre P, Vander "Self-treatment of acute migraine with subcutaneous sumatriptan using an auto-injector device - comparison with customary treatment in an open, longitudinal study.
Certain conditions can increase your risk for problems. Are you trying to become pregnant? This medication should not be taken if you have certain medical conditions. Store easy-to-lose items in the same place each time after you use them. IMITREX Injection is contraindicated.
Oral administration of sumatriptan to pregnant rabbits during the period of organogenesis resulted in increased incidences of embryolethality and fetal cervicothoracic vascular and skeletal abnormalities. Intravenous administration of sumatriptan to pregnant rabbits during the period of organogenesis resulted in an increased incidence of embryolethality. Priming Rod does not stick out and to get the Pen ready for the next use. Cardiovascular: Infrequent were hypertension, hypotension, bradycardia, tachycardia, palpitations, pulsating sensations, various transient ECG changes nonspecific ST or T wave changes, prolongation of PR or QTc intervals, sinus arrhythmia, nonsustained ventricular premature beats, isolated junctional ectopic beats, atrial ectopic beats, delayed activation of the right ventricle and syncope. Rare were pallor, arrhythmia, abnormal pulse, vasodilatation, and Raynaud syndrome.
Defects in the corneal epithelium were noted in a 60-week study. Earlier examinations for these toxicities were not conducted and no-effect doses were not established; however, the relative exposure at the lowest dose tested was approximately 5 times the human exposure after a 100-mg oral dose or 3 times the human exposure after a 6-mg subcutaneous dose. To remember a person's name, repeat it several times after being introduced. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Feeling hot or cold, weak, or "strange" in some way.